• search
For Quick Alerts
For Daily Alerts

Anti-obesity drugs dull brain pleasure centres to 'food porn'

By Nitsi

Washington, Oct 27 (ANI): Anti obesity drugs might make that pastry look a lot less appetizing, according to scientists at the University of Cambridge.

Professor Paul Fletcher and colleagues discovered that the anti-obesity drug sibutramine reduced brain responses in two regions of the brain, the hypothalamus and the amygdala, both of which are known to be important in appetite control and eating behaviour.

MRI scans revealed that in participants given sibutramine - an anti-obesity drug - the brain activity in these areas was reduced significantly.

Additionally, people who had the greatest reduction of brain activation following drug treatment tended to eat less and to lose more weight.

"Our results help us to understand more precisely how anti-obesity drugs work in the brain to change eating behaviour and hence, ultimately, to assist people in losing weight," said Professor Ed Bullmore at the University of Cambridge.

"These results remind us that the major cause of obesity in the West is over-eating, and this behaviour is regulated by reward and satiety processing circuits in the brain," he added.

The findings are reported today in The Journal of Neuroscience. (ANI)

For Daily Alerts
Get Instant News Updates
Notification Settings X
Time Settings
Clear Notification X
Do you want to clear all the notifications from your inbox?
Settings X
We use cookies to ensure that we give you the best experience on our website. This includes cookies from third party social media websites and ad networks. Such third party cookies may track your use on Oneindia sites for better rendering. Our partners use cookies to ensure we show you advertising that is relevant to you. If you continue without changing your settings, we'll assume that you are happy to receive all cookies on Oneindia website. However, you can change your cookie settings at any time. Learn more