Laser eye surgery has no long-term effects on cornea

Washington, Nov 10 (ANI): A research team, including an Indian-origin boffin, has found that laser eye surgery that corrects vision does not lead to later problems with the cornea - at least not after nine years.

Two types of laser surgery-photorefractive keratectomy (PRK) and laser in situ keratomileusis (LASIK)-are often used to correct refractive errors such as nearsightedness.

However, little is known about how these procedures affect the cornea, the transparent membrane covering the eye, on the cellular level over the long term.

Sanjay V. Patel, M.D., and William M. Bourne, M.D., of Mayo Clinic, Rochester, Minn., studied 29 eyes of 16 patients who had undergone LASIK or PRK. Photographs of the cells lining the cornea (endothelial cells) were taken and analysed before and nine years after surgery.

The annual rate of corneal endothelial cell loss in the eyes of patients who had had surgery was compared with those of 42 eyes that had not undergone either procedure.

Nine years after surgery, the density of cells lining the cornea had decreased by 5.3 percent from their preoperative state.

However, the average annual rate of cell loss (0.6 percent) was the same in corneas of eyes that were operated on and those that were not.

"Our results support the findings of numerous short-term studies that found no significant endothelial cell loss after LASIK and PRK," the authors said.

They added: "The importance of the findings in our study relates to using corneas that have undergone LASIK or PRK as donor tissue."

The study has been reported in the November issue of Archives of Ophthalmology, one of the JAMA/Archives journals. (ANI)