• search

Aprotinin not much help for Achilles tendinitis

Written by: Staff

NEW YORK Apr 8 (Reuters) Australian doctors report that for a strained or inflamed Achilles tendon, injections of aprotinin do not seem to do much to shorten recovery time.

Achilles damage is a common problem for runners, and can be difficult to treat. Symptoms can often persist for more than a year, the researchers note in the British Journal of Sports Medicine.

Because surgery and painkillers are often unsuccessful, sports medicine specialists have turned to aprotinin, a natural substance obtained from bovine lungs that may act as an inhibitor of an enzyme that breaks down collagen.

''Previous studies have shown a significant benefit,'' Dr Richard A Brown from the South Sydney Sports Medicine Center, Kensington, New South Wales told Reuters Health.

To investigate aprotinin's value in treating Achilles tendon damage, Brown and his colleagues assigned 26 patients with the condition to three weekly injections of aprotinin plus local anesthetic, or three saline plus anesthetic injections. All the patients participated in a program of eccentric exercises.

Absolute improvements in Achilles tendon symptoms were greater in the aprotinin group than in the placebo group, the researchers report, but the differences were not statistically significant at any time point up to a year after treatment.

Similarly, the researchers note, none of the secondary outcomes such as tenderness or ''number of hops to pain'' showed significant differences between the two groups.

There was a trend toward a greater occurrence of itch associated with injections in the aprotinin group, the report indicates. None of the patients experienced infections, ruptures, or other significant side effects.

''I would try eccentrics'' and other measures before using aprotinin, Brown advised.


For Daily Alerts
Get Instant News Updates
Notification Settings X
Time Settings
Clear Notification X
Do you want to clear all the notifications from your inbox?
Settings X
We use cookies to ensure that we give you the best experience on our website. This includes cookies from third party social media websites and ad networks. Such third party cookies may track your use on Oneindia sites for better rendering. Our partners use cookies to ensure we show you advertising that is relevant to you. If you continue without changing your settings, we'll assume that you are happy to receive all cookies on Oneindia website. However, you can change your cookie settings at any time. Learn more