The four players, Schalke's duo May Meyer and Leon Goretzka, Hamburg's Marcell Jansen and Augsburg's Andre Hahn, will not travel to the training camp in South Tyrol May 21, Xinhua cited from a statement by the GFA Wednesday.
Loew also said Monchengladbach's Christoph Kramer has replaced Hahn.
"This had nothing to do with Andre Hahn's performance. We were pleased with the way he presented himself," Loew said.
"But we have some players in the midfield who were recently injured or have returned from long injury breaks. We, therefore, intend to take another option into the training camp to be prepared for any event," he said.
"Christoph Kramer has left an excellent impression during the training sessions and matches," Loew added.
Loew reasoned the cuttings of the young Goretzka and Meyer: "Especially players like Leon Goretzka and Max Meyer belong to the future. They are still young, they still have many opportunities to play big tournaments."
The omission of Hamburg's Marcell Jansen has different reasons as the full back suffered an ankle injury at a friendly against Chile. "He has not had enough play time to find his rhythm."
After the 10-day preparation in South Tyrol the " Nationalmannschaft" will encounter Cameroon and Armenia for international friendlies before they leave Frankfurt for Brazil June 7. Five days ahead of the departure, Loew has to submit his final 23-men World Cup squad to the FIFA.