Manchester United manager Mourinho, who was sacked by the Blues midseason last year will be back at Stamford Bridge first time in 1 year.
Chelsea are on a high at the moment as they had picked up a comfortable win over Leicester City last week. Antonio Conte has deployed brand new tactics and playing a 3-4-3 formation. The Blues are placed in the 5th position in the league table.
Manchester United, on other hand, have had a tough start to the season so far. They are placed at the 7th position in the league table.
It will be interesting to see if Antonio Conte would change the winning combination and bring Brazilian duo Willian and Oscar who were out of the squad last week.
Cesc Fabregas and Branislav Ivanovic have been ruled out of action due to injury.
Jose Mourinho took a defensive approach as they took on Liverpool last game week. Ashley Young started ahead of Juan Mata.
Considering the magnitude of this match, the Portuguese manager is likely to maintain the same starting XI. Henrikh Mkhitaryan is yet to gain full fitness as Mourinho suggested that he need to train more to gain match fitness.
Goalkeeper: Thibaut Courtois
Defenders: Cesar Azpilicueta, Gary Cahill, David Luiz
Midfielders: Victor Moses, N'Golo Kante, Nemanja Matic, Marcos Alonso
Strikers: Pedro, Diego Costa, Eden Hazard
Manchester United (4-2-3-1)
Goalkeeper: David De Gea
Defenders: Antonio Valencia, Eric Bailly, Chris Smalling, Daley Blind
Midfielders: Ander Herrera, Marouane Fellaini; Marcus Rashford, Paul Pogba, Ashley Young
Striker: Zlatan Ibrahimovic
Chelsea 0-0 Manchester United