League leaders Chelsea who have a comfortable 9 points lead at the top will be eyeing a win against arch-rivals Arsenal and widen the gap.
Arsenal too have an uphill task on their hands to beat the mighty Blues who have been phenomenal this season. The Gunners have to win the match to remain in the title hunt.
In another important clash, Manchester United take on defending champions Leicester City who are currently struggling to fight relegations.
Leicester's journey in their title defending campaign has been horrendous and they are just 2 points above the relegation zone.
Another slip-up and Claudio Ranieri's side would go down into the bottom three.
Manchester United who managed a draw against rock-bottom side Hull City would target full three points and remain in the race of finishing top four.
Among the other big teams, Manchester City take on Swansea City and Liverpool take on Hull City and Tottenham Hotspur face Middlesbrough.
Here are all the matches from game week 24
February 4, Saturday
Chelsea Vs Arsenal - 6:00 PM (IST)
Watford Vs Burnley - 8:30 PM (IST)
Southampton Vs West Ham United - 8:30 PM (IST)
Everton Vs Bournemouth - 8:30 PM (IST)
West Brom Vs Stoke City - 8:30 PM (IST)
Hull City Vs Liverpool - 8:30 PM (IST)
Crystal Palace Vs Sunderland - 8:30 PM (IST)
Tottenham Vs Middlesbrough - 11:00 PM (IST)
February 5, Sunday
Manchester City Vs Swansea City - 7:00 PM (IST)
Leicester City Vs Manchester United - 9:30 PM (IST)