Two of the finest tacticians in world football Antonio Conte and Pep Guardiola lock horns at the Etihad stadium to decide who will be at the top of the league table.
Chelsea are currently leading the charts with 31 points from the first 13 matches. They are in a fine form at the moment and are on a seven-match winning streak.
Manchester City are third in the table with 30 points tied with Liverpool. A win against the Blues at their home ground would do a world of good to Guardiola's men.
Among other important clashes this weekend, Arsenal take on West Ham United, Manchester United take on Everton and Liverpool face AFC Bournemouth.
Here are all the matches from game week 14:
Saturday, December 3
Manchester City Vs Chelsea - December 3 - 6:00 PM (IST)
Sunderland Vs Leicester City - December 3 - 8:30 PM (IST)
Tottenham Vs Swansea City - December 3 - 8:30 PM (IST)
Crystal Palace Vs Southampton - December 3 - 8:30 PM (IST)
Stoke City Vs Burnley - December 3 - 8:30 PM (IST)
West Bromwich Albion Vs Watford - December 3 - 8:30 PM (IST)
West Ham United Vs Arsenal - December 3 - 8:30 PM (IST)
Sunday, December 4
Bournemouth Vs Liverpool - December 4 - 7:00 PM (IST)
Everton Vs Manchester United - December 4 - 9:30 PM (IST)
Monday, December 5
Middlesbrough Vs Hull City - December 5 - 1:30 AM (IST)