Sunit Sangwan (82kg) and Manoj Kumar (64) lost their men's quarter-final bouts while Pooja Rani was beaten in the women's 75 kg round of 16 by better-rated England's Savanna Marshall 3-0.
Sangwan began well his bout with David Nyika of New Zealand by winning the first round, but was at the receiving end in the next two.
Manoj went down tamely to England's Samuel Maxwell.
Pooja was a clear-cut loser against Marshall with all three judges giving a unanimous decision.
It was a disappointing end to the day after veteran L Sarita Devi outpunched Nigeria's Kehinde Obareh 2-0 to advance to the quarterfinals in the women's 57-60kg. The 32-year-old Manipuri boxer won both her rounds convincingly.
Sarita's quarter-final opponent Friday is Charlene Jones of Wales.