59-year-old Manohar, who quit after serving only eight months in office, cited personal reasons for his decision.
He was was elected unopposed as the ICC's first independent chairman in May 2016 for a two-year term.
He is said to be chiefly responsible for trying to reduce the influence wielded by the Big Three, has resigned from his post as ICC chairman. He had resigned as the chairperson of the Board of Control for Cricket in India (BCCI) in May, last year.
However, his relationship with the BCCI was not good.
Cricket world was in a state of shock after Manohar's surprise resignation and wondered what could be the possible reason for him to quit.
Here's how people reacted on Twitter:
Veteran cricket commentator Harsha Bhogle termed Manohar's decision as 'unpredictable'.
Harsha Bhogle ready to give Shashank Manohar the benefit of doubt.
Reaching Shashank Manohar is harder than contacting former India captain MS Dhoni, feels Ayaz Menon.
This is how senior journalist Shekhar Gupta reacted after Shanshank Manohar's resignation.
This is what BBC journalist Sameer Hashmi had to say on Shashank Manohar.
This is how a fan reacted
Manohar quits on 140th anniversary of first Test cricket match.