Asked about whether it's about time that Virat Kohli handed over the top job in ODIs, Kirsten was non-committal.
"You are not going to get an answer out of me. You replace MS Dhoni at your peril, because the one experience I have had is that all great leaders have great performances till the end of their careers," said Kirsten at a promotional event.
Kirsten said that if one is willing to let Dhoni go, one never knows if India misses out on some potential match-winning performances in 2019 World Cup in United Kingdom.
"So, if you (are) willing to let MS Dhoni go when there might potentially be a great World Cup performance left in him if he goes to the (2019) World Cup, which I am not sure if he is (taking part in) or not, you take the risk of doing that," the former South Africa cricketer said emphatically.
Terming Dhoni as a "great player", Kirsten slammed his critics, saying those doubting his ability are making a mistake.
"I think that is the question I get asked the most everytime I come to India. My answer hasn't changed in three years. That he (Dhoni) is definitely the best leader I have ever worked with. And his record for Indian cricket over the last nine-ten years speaks for itself," said the South African when asked about the debate surrounding Dhoni's future.
"There is no debating in my opinion that he is up there with India's greatest captains and certainly has produced the trophies for India in his time," added Kirsten who was India's coach when Dhoni and company lifted the World Cup in 2011.
According to the former South Africa batsman, Dhoni's record in limited overs cricket spoke for itself.
"You just have to look at his ODI batting record as well. As a finisher, it's unsurpassed in the world in terms of the position he bats in. So, if anyone is doubting his ability, I think they would be making a great mistake.
"He is a great player and all great players would continue to produce fantastic performances through their career. It's exciting to see him doing well and having success with the Indian team. I enjoyed working with him and it was a great experience for me," he added.
Kirsten spoke to media persons after overseeing a cricket camp organised by Saldhana International Academy at the Mumbai Police Gymkhana here.
Kirsten felt it should be left to the Ranchi star to decide on his future.
"There comes a time in every player when he is got to consider for himself whether he should be in the team or it's time to move. We will leave the decision up to him," he said.
To a query whether Dhoni should consistently bat higher up the order as he did in the recently concluded ODI series against New Zealand when he batted at no.4, Kirsten said he was capable of batting in a lot many positions.
"That discussion is going on for eight years. He does (have) an ODI batting average of over 50. He can bat in lot of different positions.
"When I was with the Indian team, I encouraged rotational batting order, where we batted according to the situation rather than this is your batting position today. MS was brilliant at that, he didn't mind where he batted."
"I always liked him to come in when we needed 100 runs to win because there was no one better (than him) in the world (who) could have won a game from that position, speaking from my experience. But he often liked to get up little bit earlier, so that he can have more time at the wicket and help himself to a hundred. MS Dhoni could pretty much bat anywhere in the batting order," Kirsten explained further.
On Anil Kumble's appointment as India'a head coach, Kirsten said, "One needs to really understand that coaching space and what value you can add to a group of people. Every environment can be different. Anil is a great human being and has got a fantastic value system.
"I worked little bit with him in the Indian team. He has been a great player with tremendous results. He will get natural respect from the players. It is also nice to have an Indian as the India coach.
"He has had immediate success and that is not surprising. No doubt he has all the credentials necessary for taking the team forward with Virat Kohli as the leader of the (Test) team and MS in white ball (ODI) formats."
Kirsten gave thumbs up to the DRS which BCCI has decided to use during the upcoming Test series against England after having consistently opposed it in the past.
"If they (BCCI) are going to try it, its brilliant. It is a great technology, and it's got better and better. It will be great for every Test playing country to use the technology".