The State Department has amended LeT's designations to add the aliases: JuD, Al-Anfal Trust, Tehrik-e-Hurmat-e-Rasool and Tehrik-e-Tahafuz Qibla Awwal, an official statement said.
Simultaneously, the Department of the Treasury targeted the financial and leadership networks of LeT by designating Nazir Ahmad Chaudhry (Ahmad) and Muhammad Hussein Gill as Specially Designated Global Terrorists (SDGTs).
Ahmad and Gill are being designated for acting for or on behalf of LeT, a terrorist organisation based in Pakistan.
Treasury and the Department of State have designated 22 individuals and four entities associated with LeT.
The Department of the Treasury targeted LeT's financial and leadership networks
"In targeting Lashkar-e-Taiba leadership, today's action demonstrates our unrelenting commitment to combating terrorism by disrupting terrorist groups' financial activities," said the Under Secretary of Treasury for Terrorism and Financial Intelligence David S Cohen.
"We will continue to target LeT's financial foundation to disrupt and impede its violent activities," he added.
LeT was responsible for the deadly November 2008 terrorist attack in Mumbai that claimed 166 lives and injured more than 300.
The group's leader is Hafiz Saeed is also a designated terrorist leader.
Ahmad has been an LeT senior leader since the early 2000 and has served as its vice-president, member of the group's central leadership and as close aide of its leader Muhammad Saeed.
Ahmad directed the group's public relations department for at least ten years and as of 2012 was the head of LeT's information wing.
Ahmad has also been a key strategist for the group and has been involved in LeT operational finance matters.
Gill is a senior LeT shura member and was an LeT founder.
He has been an accountant for LeT for more than ten years and has served as its chief financial officer and headed its accounts department for several years.
He also has served in LeT's revenue wing and has maintained its expense records.
"As a result of today's action, all property and interests in the United States or in the possession or control of US persons in which Ahmad and Gill have an interest are blocked and US persons are prohibited from engaging in transactions with them," the Treasury said.