He also called the upcoming Trump Administration "to avoid things spiralling out of control".
"When China feels questioned on its unity, that's not exactly very clever," Ayrault was quoted by Xinhua news agency.
"China is a big country. We can have our differences with China, but you don't talk to a partner like that." "I hope that the new team will have learnt enough so that we manage an uncertain world with more sangfroid and responsibility," the French top diplomat added.
On "Fox News Sunday" programme, Trump said that he does not feel "bound by a one-China policy unless we make a deal with China having to do with other things, including trade."
The inappropriate rhetoric came just days after Trump held a phone call with Taiwan leader Tsai Ing-wen, breaking decades of US diplomatic policy.