The convoy is likely to leave for Madaya, a Syrian town under government siege. People living in the area reported to have been eating cats and grass to survive.
"We are pretty confident," reported the BBC citing UN refugee agency spokesperson Melissa Fleming as saying.
According to reports, at least 23 people including infants have been died of starvation in Madaya near Lebanon's border since December, 2015.
The area has not received food supply since October last year due to the siege of Assad forces and Hizbollah.
"I have just got confirmation that our humanitarian convoy will leave tomorrow (Monday) morning," added Fleming.
"This is typical that it takes a while - the administrative hurdles are constant," she added.
Syria's ongoing civil war is the worst humanitarian crisis of our time. Half the country's pre-war population more than 11 million people have been killed or forced to flee their homes.