The "spacecraft will impact the planet at more than 8,750 miles per hour on the side of the planet facing away from Earth," NASA said in a statement on Thursday. "Due to the expected location, engineers will be unable to view in real time the exact location of impact," Xinhua reported.
Launched in August 2004, MESSENGER traveled 7.9 billion km on a journey that included 15 trips around the sun and flybys of Earth once, Venus twice and Mercury three times.
The spacecraft began orbiting Mercury in March 2011.
The four- year mission was blessed with many scientific findings, including one in 2012 that provided compelling support for the hypothesis that Mercury harbors abundant frozen water and other volatile materials in its permanently shadowed polar craters, and also helped test many technological achievements, including the development of a vital heat-resistant and highly reflective ceramic cloth sunshade that isolated the spacecraft's instruments and electronics from direct solar radiation, vital to mission success given Mercury's proximity to the sun.