The investigation that led to recovery of remains of missing climbers was started in September last year after a climber spotted skeletal remains and climbing equipment at the foot of the Mattherhorn glacier.
"The remains of the two climbers have been found, police said, 45 years after they went missing.
The remains of missing climbers were found at about 2,800 meters (9,200 feet).
The remains, officials confirmed, were Michio Oikawa and Masayuki Kobayashi, two climbers who were 22 and 21 years old when they went missing in August 1970, Japan's Foreign Ministry said.
The 4,480-meter Matterhorn is among the most well-known peaks in Europe.