Xi and his wife Peng will be in India on a three-day visit that begins Wednesday in Ahmedabad.
On Thursday, the Chinese president travels to New Delhi.
Peng will visit Tagore International School Thursday morning, said school principal Madhulika Sen.
"The Chinese first lady will spend about 45 minutes in the school," Sen told IANS.
She said that a cultural programme, which includes song and dance, will be presented.
Peng will interact with a select group of students and teach them calligraphy.
Sen said their school has a special tie-up with a Chinese school, through which they teach Kathak and Yoga to the Chinese students while the Chinese teach them Tai Chi and calligraphy.
Peng Liyuan, 51, is a singer, popularly known in China for her patriotic folk songs. Peng was born to a family of artists in Shandong province. Her mother was a member of a local art troupe and her father was a curator of local museum.
She holds a Master's degree in traditional ethnic music and now serves as the dean of the Art Academy of the People's Liberation Army. She holds the rank of a major general.