The fourth seeded Indo-Czech pair defeated the World No. 5 combination of Pakistan's Aisam-ul-Haq Qureshi and his partner Netherland's Jean-Julien Rojer 6-1, 6-7, 6-4 on Tuesday.
Indo-Czech pair will face top seeded Bryan brothers in their semifinal match.
The Indo-Czech pair will now face top-seeded American brothers Mike and Bob Bryan, who defeated 12th-seeded British pair of Colin Fleming and Jonathan Marray 7-6 (7), 6-4 in their quarterfinal match.
Meanwhile India's Sania Mirza along with her Chinese partner Zheng Jie will be facing Hsieh Su-wei of Taiwan and Peng Shuai of China in their quarterfianl match later today.
US Open Results:
Women's Singles quarter-finals:
1. Serena Williams (1) defeated Carla Suárez Navarro (18) 6-0, 6-0
2. Li Na (5) defeated Ekaterina Makarova (24) 6-4, 6-7 (5/7), 6-2