Many are said to be trapped inside buildings. Strong hailstorm was also reported.
Forecasters say up to 53 million people could be affected, reports BBC news. The fast-moving storm with a speed of 111km/h (68mph) - is moving its way east, the report says.
An alert has been issued by the National Weather Service warning people that severe thunderstorms, strong winds, tornadoes and hails are expected in several states.
(With agency inputs)