"On the auspicious occasion of Ram Navami, I convey my greetings and good wishes to all my fellow countrymen," the president said in his message.
"Maryada Purushottam Shri Ram is the embodiment of selfless service and the highest moral and ethical principles. May the celebrations inspire us to model our lives on the life and deeds of Shri Ram," he added.
Mukherjee said: "Let us strive to spread his noble message of righteous conduct and rededicate ourselves to building a great nation."
Ram Navami will be celebrated across India on Tuesday.