The trucks are loaded with construction material and consumer items and were coming from West Bengal, Assam and Meghalaya to Manipur.
Their movements have been hit since Wednesday night, the officials said. Trucks going from Imphal to other states were also stranded along with buses and private cars.
District officials told IANS over the phone that if there were more rains in the coming days, the situation would worsen.
Officials and labourers of the Border Roads Organisation are working round the clock to clear the landslides.
The stranded motorists and passengers were facing major problems, including shortages of food, on the hilly highway, the officials said. The women passengers battled with lack of privacy.
The National Highway 37 passing through Tamenglong, Imphal East and Imphal West districts is one of the two lifelines of Manipur.