A mistake from goalkeeper Wojciech Szczesny allowed Karim-Richards to score the decisive goal. Arsenal fans booed off players following their FA Cup exit and furious manager Arsene Wenger lashed out at his players after the poor show on the pitch.
A bigger task awaits Arsenal when they face German league leaders and last year's runners-up Bayern Munich in the UEFA Champions League last 16 clash on Tuesday. The Gunners are not at all favourites to win the competition and could head towards their eighth season without any silverware.
The Premier League title is out of their reach, the Champions League is a tough ask, they are out of the FA Cup and also the defeat to bradford earlier in December saw them crashing out of the Capital One Cup.
Fans have reportedly called for a protest next on Tuesday and Saturday in the eighth minute of the Champions League clash against Bayern Munich and the Premier League clash on Saturday against Aston Villa.
Wenger is paying the price for not bringing in reinforcements during the January transfer window. Fans also took a dig at the management for not spending enough money on players and only concentrating on making profits.
After the defeat to Blackburn Wenger admitted his side are not matured enough and also lack world-class talent.
Arsenal have been linked with Liverpool goalkeeper Pepe Reina as a replacement for Szczesny. The 22-year old Pole hasn't been in great form lately while Wenger also target Stoke's Asmir Begovic, Sunderland's Simon Mignolet and Michel Vorm from Swansea City.
As fans call for 'Wenger out' Arsenal's hierarchy are in no hurry to sack their manager.
Wenger was handed a £70million transfer budget in January as the Gunners were linked with Barcelona striker David Villa, Fiorentina's Stevan Jovetic, Atletico Madrid's Adrian and Borussia Dortmund playmakers Marco Reus and Mario Gotze.
Arsenal face a daunting task against German giants on Tuesday night at the Emirates and if Arsenal do not make it to the Champions League next season, it could Wenger's last days at the Emirates.