Black Cats have won just two league games so far and are only two points clear of the relegation zone. But all eyes will on Redknapp who admitted this is the toughest phase of his career with the Rangers having only 4 points in 13 games.
Sunderland captain Lee Cattermole is sidelined due to a knee injury and defender John O'Shea suffered a calf injury during the loss against West Brom Albion.
Rangers welcome back captain Park Ji-sung is likely to start in Redknapp's first game while Jose Bosingwa could return to the starting XI.
*QPR have not won any of their last five visits to Sunderland.
*Sunderland did the double over QPR last season.
Sunderland (4-4-2): Mignolet-Bardsley, Kilgallon, Cuellar, Rose-Johnson, Larsson, Cattermole, McClean-Sessegnon-Fletcher.
Queens Park Rangers (4-2-3-1): Julio Cesar-Bosingwa, Mbia, Nelsen, Traore-Diakite, Faurlin; Granero, Park, Hoilett-Cisse.