Both teams have injury concerns especially to important players returning from international duty during the midweek break.
Everton midfielder Darren Gibson is out for five to six weeks with a thigh strain suffered on international duty with the Republic of Ireland.
The Toffees' deadline-day signing Bryan Oviedo is not yet eligible to play in England as he requires work permit and paper work to be done.
Newcastle manager Alan Pardew will have to cope without several injured players. Goalkeeper Tim Krul could miss a couple of games due to an elbow injury which he sustained during training with the Netherlands.
Centre-back Fabricio Coloccini is a major doubt after returning from Argentina with a hamstring strain. Toons midfielder Cheick Tiote has been doubtful since the start of the new season while Danny Simpson, Ryan Taylor, Haris Vuckic and striker Shola Ameobi are also out.
*Newcastle need to score just one goal to reach 1,000 in the Premier League.
*Newcastle have failed to keep a clean chit this season.
Everton (4-4-1-1): Howard-Neville, Jagielka, Distin, Baines-Naismith, Gibson, Fellaini, Pienaar-Osman-Jelavic.
Newcastle United (4-3-3): Krul-Gutierrez, Coloccini, S Taylor, Santon-Tiote, Cabaye, Anita-Ben Arfa, Cisse, BA.