Roberto Di Matteo's men are the only side with a 100% record this season while QPR have managed just a single point in three games.
Mark Hughes is free of injury concerns but Samba Diakite is unavailable while defender Stephane Mbia is out injured.
The Blues defensive duo John Terry and Ashley Cole are likely to return after missing out England's World Cup qualifiers. Terry will face QPR defender Anton Ferdinand for the first since being acquitted of racially abusing the Rangers defender.
German winger Marko Marin will have to wait for his Premier League start despite playing for the reserves.
*Chelsea have won their last four Premier League games.
*QPR's opening day 5-0 loss ended their five-match unbeaten run at Loftus Road.
Queens Park Rangers (4-4-2): Green-Bosingwa, Ferdinand, Onouha, Fabio-Wright-Phillips, Granero, Faurlin, Hoilett-Zamora, Johnson
Chelsea (4-2-3-1): Cech-Ivanovic, Cahill, Luiz, Cole-Lampard, Mikel-Ramires, Mata, Hazard-Torres