Both teams reached the semis for the first time after the 1968 Games in Mexico City. Japan emerged winners by beating the hosts 2-0 to claim Bronze.
Mexico topped their Group after beating Gabon and Switzerland but managed a draw against South Korea to go through to the quarter-final. In the quarters, they beat Senegal 4-2 after extra time was required to decide the winner.
Meanwhile, Japan have not conceded a single goal at the Games. They shocked Spain, beat Morocco and drew with Honduras before comfortably thrashing Egypt 3-0 in the quarter-finals.
Japan beat Mexico 2-1 in a warm-up match prior to the games at Nottimgham Forest's City Ground. Both teams can size up each other and get set for an even contest yet again at the iconic Wembley stadium.
Japan have the defensive stabilty while the Mexican's are more creative in midfield. Both teams will battle to control possession especially in midfield and restrict each other for long shots.
Giovani dos Santos, Hector Herrera and Marco Fabian played key roles to snatch an extra time over Senegal while Yuki Otsu, Kensuke Nagai have been impressive in their teams 3-0 win over Egypt.
Kick-Off at 09:30 PM IST on 7th August, New Wembley Stadium, London.
Mexico (4-4-2): Corona-Jimenez, Salcido, Mier, Chavez, Reyes-Aquino, Enriquez, Fabian-Dos Santos, Peralta.
Japan (5-4-1): Gonda-Tokunaga, Ogihara, Sakai, Yoshida, Suzuki-Otsu, Higashi, Yamaguchi, Kiyotake-Nagai.