Ferguson said that reclaiming the title was 'priority number one' after rival neighbours Manchester City stole the title from United during injury time last season.
City beat QPR (Queens Park Rangers) 3-2 thanks to Edin Dzeko's and Sergio Aguero's injury-time goals on the last day of the season. City claimed the title on goal difference even though United beat Sunderland 1-0.
"I want to recover the title after the disappointment of last season," Ferguson said ahead of their first pre-season match on Wednesday against South Africa's AmaZulu FC.
"We either win the title or come second -- it is an important part of the history of our club over the past 20 years," Ferguson said.
"United have to recover as the club have done so many times in the past. That is our target this year. Priority number one is to win the English Premier League title back," the 70-year-old said.
United have been busy during the summer transfer window acquiring Japanese star Shinji Kagawa and youngster Nick Powell. The Old Trafford club have also shown interest in Arsenal's want-away striker Robin van Persie while they target 19-year-old Brazilian Lucas Moura.
Ferguson also illustrated the resilience of the Red Devils by explaining a bit of their successful history.
"When Arsenal won the title from us in 1998, we won the treble the following year. Then Chelsea came along and got off to a flier in the league for the first two years so we changed our pre-season a little to ensure quick starts," Ferguson said.
Meanwhile, few United stars like Wayne Rooney, Ashley Young and Danny Welbeck have been rested after their Euro 2012 campaign while others like Ryan Giggs are preparing for the upcoming London Olympics and with captain Nemanja Vidic injured, United have to manage with a young inexperienced side led by Rio Ferdinand in South Africa.
But the Red Devils boss is confident his young side can compete against AmaZulu, "When I started picking young players, we played Port Vale in a League Cup game and an MP protested to the government, saying we were cheating the public and they wanted their money back."
"Little did she know she was watching perhaps the greatest group of young players to come through at a football club in England. The same applies here," he said.