Gilani's visit is being billed as the most significant by a Pakistan leader in recent times as it comes at a time when a Pakistan is locked in a tense stand off with long time ally the US.
"The visit assumes added significance in view of the ongoing developments in the region," Rong Ying, Senior Research Fellow at the state-run Chinese Institute of Strategic Studies told PTI, referring to the US-Pakistan tensions in the aftermath of bin Laden's killing by US troops.
China-Pakistan relationship is important and significant from its own perspective and history, he said.
High level visits by Pakistan to China are frequent considering their close strategic relations. President Asif Ali Zardari has visited China five times since he assumed office in 2008.
But Gilani's visit this time is attracting more than usual attention even though it was worked out earlier.
Pakistan is facing internal turmoil after the US raid that killed bin Laden early this month and unrelenting pressure from the US to crack down on top Taliban leaders and other militant groups.
Gilani is therefore expected to seek stronger support from China at a time when Pakistan is facing intense international scrutiny and pressure, reports said.
Besides holding talks with Chinese President Hu Jintao and Premier Wen Jiabao Gilani, Gilani will during his four-day visit also kick off events being organised to celebrate the 60th year of establishment of diplomatic ties between the two countries.
He will land in Shanghai tomorrow and go to Suzhou to address the first conference of World Cultural Forum. He would later arrive in Beijing along with his high powered delegation for talks with Chinese leaders.
A number of agreements in the fields of economy, trade, finance and culture were expected to be signed during the visit, according to officials on both sides.
For its part China has already extended its full backing to Pakistan after bin Laden''s death, praising Islamabad's contribution to terror and backing its demand that US should respect its sovereignty and territorial integrity.
At the same time China also called for united global efforts to fight terrorism.