Washington, Dec 16 (ANI): Exposure to bisphenol A (BPA) may compromise the quality of a woman's eggs retrieved for in vitro fertilization (IVF), a small-scale University of California, San Francisco-led study found.
As blood levels of BPA in the women studied doubled, the percentage of eggs that fertilized normally declined by 50 percent, according to the research team.
The chemical BPA, which makes plastic hard and clear, has been used in many consumer products such as reusable water bottles. It also is found in epoxy resins, which form a protective lining inside metal food and beverage cans.
"While preliminary, the data indicate the negative effect of BPA on reproductive health and the importance of allocating more funding to further investigate why such environmental contaminants might be disrupting fertility potential," said Victor Y. Fujimoto, MD, lead study author and professor in the UCSF Department of Obstetrics, Gynecology, and Reproductive Sciences, who also is on the faculty of the UCSF Center for Reproductive Health.
In the study, BPA levels and fertilization rates were analyzed for 26 women undergoing IVF during 2007 and 2008 at the UCSF Center for Reproductive Health. The women were a subgroup of a larger study evaluating the effect on reproductive health of trace exposures to toxic metals - mercury, cadmium and lead.
Findings are available online in the journal Fertility and Sterility. (ANI)