Washington, Oct 28 (ANI): A Kaiser Permanente study found that increasing urine BPA (Bisphenol-A) level was significantly associated with decreased sperm concentration, decreased total sperm count, decreased sperm vitality and decreased sperm motility.
The five-year study, published in the journal of Fertility and Sterility, recruited 514 workers in factories in China and compared workers who had high urine BPA levels with those with low urine BPA.
Men with higher urine BPA levels had 2-4 times the risk of having poor semen quality, including low sperm concentration, low sperm vitality and motility.
This is the first human study to report an adverse association between BPA and semen quality. Previous animal studies found a detrimental association between BPA and male reproductive systems in mice and rats.
This study is the third in a series, published by Dr. Li and his colleagues, that examines the effect of BPA in humans.
The first study, published in November 2009 in the Oxford Journals Human Reproduction, found that exposure to high levels of BPA in the workplace increases the risk of reduced sexual function in men.
The second study, published in May 2010 in the Journal of Andrology, found that increasing BPA levels in urine are associated with worsening male sexual function.
The new study adds to emerging human evidence questioning the safety of BPA, a chemical created in the production of polycarbonated plastics and epoxy resins found in baby bottles, plastic containers, the linings of cans used for food and beverages, and in dental sealants. (ANI)