The World Cup hero Andres Iniesta and Liverpool striker Fernando Torres were out of the team due to injuries. The team coach Vicente del Bosque has been forced to make several modifications to the World Cup winning squad.
Young midfielder Javi Martinez was omitted after being called up to the U-21 side for a European Championship qualifier against Finland.
Goalkeeper Pepe Reina and centre-back Raul Albiol were also been excluded from the squad.
Villarreal defensive midfielder Bruno Soriano and left-back Nacho Monreal were called in to the final squad.
The friendly match will be Spain's first match after winning the World Cup in South Africa.