The company said the it would incur between $65 million and $71 million in restructuring charges because of the layoffs.
Adobe employed 7,564 people worldwide at the end of Aug 2009.
The company also said that they would only cut jobs from their own operations and not from Omniture which they acquired last month.
Adobe Systems is known for its Photoshop editing programme and Acrobat document software. It also produces the Flash and Shockwave software used in many games and Internet applications.