"I have absolutely no interest in running for president again," Clinton said to a TV interview.
"No. None. I know that"s hard for some people to believe. But, you know, I just don't," Clinton told ABC News.
Clinton said she was at first skeptical when she got a call from Obama asking her to be secretary of state just days after the Nov 4, 2008 presidential election.
"Obama said, 'I want you to be my secretary of state, I said, Oh, no, you don't, " Clinton said.
Clinton said that her current job as the top US diplomat 'is incredibly, all-encompassing' and that when it is over, she may look forward to 'taking some time off'.