The blaze was reported from the third floor of Anusandhan Bhavan at 07:06 PM when senior Ministry officials were present in the building
The officials rushed out of the building as soon as the fire alarm rang and the fire brigade rushed to the spot.
Though the fire was doused withing two hours, four persons were trapped on the fourth floor of the building and rescued after three hours.
A senior police officials said, "Out of the persons rescued, two were brought dead at hospital." He also said, "These people were on the third floor when the fire broke out. In a bid a escape, they ran to the fourth floor where they got trapped."