New species of bacteria found in human mouth

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Washington, Aug 11 : Researchers at King's College London Dental Institute have discovered a new species of bacteria in the mouth - a finding that could help scientists to understand tooth decay and gum disease and may lead to better treatments.

Tooth decay and gum disease are the most common bacterial diseases of man and are caused by changes in the microbes normally present in the mouth.

To gain a better understanding of these diseases, scientists first need to know which bacteria are present in human mouths.

"The healthy human mouth is home to a tremendous variety of microbes including viruses, fungi, protozoa and bacteria," said Professor William Wade from King's College London Dental Institute.

"The bacteria are the most numerous: there are 100 million in every millilitre of saliva and more than 600 different species in the mouth. Around half of these have yet to be named and we are trying to describe and name the new species," he added.

While studying healthy tissue as well as tumours in the mouth, researchers found three strains of bacteria called Prevotella that could not be identified.

Prevotella species are part of the normal microbial flora in humans and are also associated with various oral diseases and infections in other parts of the body.

The researchers named the new species Prevotella histicola; histicola means 'inhabitant of tissue'.

"Interestingly, this species was isolated from within the oral tissues, both in oral cancers and normal, healthy tissue. This confirms other work showing that oral bacteria can invade both tissues and individual cells," said Wade.

Understanding the composition of the oral microbiota will help scientists devise new prevention measures and treatments for oral diseases.

"A detailed description and name for each species of bacteria are needed so that different laboratories can recognise all of the bacterial species present in the mouth," said Wade.

The study is published in the August issue of the International Journal of Systematic and Evolutionary Microbiology.

ANI

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